Hemophilia is an exampleof an X-linked hereditary disease. Queen Victoria of England was a carrier, and?

through her children she spread the gene to several other royal houses in Europe.


1) If you were a member of one of these families, what would be some implications?


2) If hemophilia had been trasmitted as a recessive trait, rather than an X-linked one, what would have been the implications for the European aristocracy?


3) Why are there so many more male than female hemophiliacs.





Please help. Serious answer only

Hemophilia is an exampleof an X-linked hereditary disease. Queen Victoria of England was a carrier, and?
1) If she spread the gene to other families then there would be a history of hemophilia in your males.





2) This question isn't clear because hemophilia IS recessive, but it's also sex linked. If hemophilia wasn't sex linked at all then there would be approximately the same risk of males and females getting the disease, but this risk would be drastically lowered. In fact, it would be the same risk factor as a woman inheriting a sex linked recessive disease. The reason is that women have 2 X chromosomes, just like all their others.





3) There are more male hemophiliacs because in males, only one allele for the disease is necessary to exhibit the trait. That's because it's recessive and if a female had a single recessive gene, that would not be enough to exhibit the trait.
Reply:this is just my opinion, as for doing your homework for you, you will still need to verify any opinions you get here. Even if you get the same opinion several times.


1) The implications would be that there is a 50% chance ofyour male offspring haveing hemophilia. The chances of female offspring would be higher, but not 50%.


2) Hempohilia is x-linked, there isn't the option of it being recesive trait because it is x-linked.


3) because it is x-linked if the x chromosome the male has is hemophiliac, the male will have it. with women if one is hemophiliac and the other is normal they will be a carrier but not have it themself. such as queen victoria. she can pass it to her children, but there is only 50% chance it will be passed on because one of her x's are normal and one is not.
Reply:Here are the facts. A female carrier has 2 Xs one good, one bad. If a male child gets the bad one he bleeds to death early in life before he can be a father. If he hasn't bled to death he has a good X. If the trait were autosomal recessive then the possible genotypes would be CC, Cc and cc. All the cc's would bleed to death so the population would tend to be CC and Cc.





You now can answer the last of the question based on the facts.