Thursday, August 19, 2010

How can I determine whether a trait is sex-linked or not?

i am given phenotypes of the P generation, the F1 and F2.





for example, 3 males with yellow eyes X 3 females with normal eyes





produce





42 males with yellow eyes


29 females with yellow eyes


10 females with normal eyes


30 males with normal eyes





that's just an example. how do i determine wether the yellow eyes are a sex-linked triat?

How can I determine whether a trait is sex-linked or not?
Sex linked simply means carried on the X chromosome.





Typically, most examples of sex linked genes are recessive, and show up MORE commonly in males, since they only have 1 X chromosome.





However, the reverse applies also- if a sex linked gene were dominant, you would see it MORE commonly in females, since they have 2 chances to get it.





That said- look at your proportions- 50% of the pups have yellow eyes, total. Looking by sex, yellow eyes is present roughly 55-45 in males.





However, it is 75-25 in females.





I would suspect that this gene could be sex linked dominant.





That said, you have way too small of a population to say anything definitive.
Reply:i don't know how to prove it but 10 females with normal eyes, that looks a bit low compared to the other phenotypes
Reply:I'm pretty sure sex-linked traits can only be carried by males since they are XY. So if you have any females with the problem then it probably isn't sex-linked.


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